PALMOPLANTAR PUSTULAR PSORIASIS INDUCED BY ADALIMUMAB A CASE REPORT AND LITERATURE REVIEW

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Psoriasis is a chronic condition of still uncertain cause. For some medications such as lithium, beta-blockers, and imiquimod, a direct drug effect is suspected. Geller L, Kellen R. Her skin eruptions improved, but her joint disease flared. Results of immunohistologic investigations.

She has not had a relapse of her psoriasis despite continuation of etanercept therapy. Increased clinical awareness for medication-related causes of psoriasis induction or exacerbation should result in earlier recognition and treatment, which ultimately would lead to a better management in psoriasis treatment. Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. By accessing the work you hereby accept the Terms. For instance, psoriasiform skin lesions may miss well-demarcated borders or lack the coarse scaling typical of psoriasis. Sign in to save your search Sign in to your personal account.

The following keywords were used: Alternatively, the induced psoriatic skin lesions can persist ie, drug-aggravated psoriasis. Histopathological examination c showing hyperkeratosis, parakeratosis, regular acanthosis with subcorneal pustules a: Tumor necrosis factor antagonist-induced psoriasis in a 3-year-old boy with Kawasaki disease.

palmoplantar pustular psoriasis induced by adalimumab a case report and literature review

Adalimumab in the management of palmoplantar psoriasis. For most drugs, however, the evidence is limited to anecdotal reports. Olteanu R, Zota A. One patient required psoralen UV-A therapy to control her psoriasis, and another used acitretin in combination with topical therapy.

Psoriasiform diaper rash possibly induced by oral propranolol in an month-old girl with infantile hemangioma. The available evidence is limited predominantly to anecdotal single-case reports or retrospective case series. Clinical images a and b showing multiple hyperkeratotic plaques over both feet with few dried pustules. Treatment with interferon-beta is indicated for multiple sclerosis.

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New-onset psoriasis in a patient treated with interferon beta-1a.

Palmoplantar pustular psoriasis induced by adalimumab: a case report and literature review.

Other clinical presentations included guttate and plaque psoriasis on the trunk and extremities and scalp psoriasis. Purchase access Adaimumab to JN Learning for one year. Palmoplantar pustular psoriasis induced by adalimumab: Waqar S, Sarkar PK.

palmoplantar pustular psoriasis induced by adalimumab a case report and literature review

The etiology of psoriasis is multifaceted. Another drug that is literture linked to an increased risk for psoriasis is terbinafine, a synthetic antifungal agent.

palmoplantar pustular psoriasis induced by adalimumab a case report and literature review

More recent associations have been reported for targeted treatments using monoclonal antibodies or small molecules that are used in oncology and immunology. Other clinical presentations included guttate or plaque psoriasis on the trunk and extremities, flexural psoriasis, scalp psoriasis, and nail disease.

Palmoplantar pustular psoriasis induced by adalimumab: a case report and literature review.

Register for email alerts with links to free full-text articles Access PDFs of free articles Manage your interests Save searches and receive search alerts. Traditionally, drugs that are strongly implicated in psoriasis include beta-blockers, lithium, synthetic antimalarial drugs, and imiquimod.

Female sex and smoking were more frequently lnduced with TNF-alpha inhibitor-induced psoriasis. Sign in to download free article PDFs Sign in to access your subscriptions Sign in to your personal account.

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Drug-induced psoriasis: clinical perspectives

However, the associations between specific drugs and psoriasis development have not been studied systematically. J Investig Allergol Clin Immunol. Create a personal account to register for email alerts with links to free full-text articles. In addition, the latency period between start of the medication and onset of psoriasis can be significantly long for some drugs. Incidence, clinical characteristics, and management of psoriasis induced by anti-TNF therapy in patients with inflammatory bowel disease: The development of this so-called paradoxal psoriasis — given that TNF-alpha antagonists are applied as biological treatment for psoriasis — is well-documented for nondermatological indications of anti-TNF-alpha antagonism, such as inflammatory bowel disease and rheumatoid arthritis.

Severe infliximab-induced psoriasis treated with adalimumab switching. How to cite this URL: Recognizing potential drug-related psoriasis is of clinical relevance to allow an optimal management of psoriasis.

The anti-PD1 drugs nivolumab and pembrolizumab are immune checkpoint inhibitors that are used in oncology.